Thymosin Alpha-1 is a synthetic version of the naturally occurring immunomodulatory peptide originally isolated from the thymus gland. This 28-amino acid peptide has been extensively studied for its role in immune system regulation and T-cell function enhancement. Our research-grade Thymosin Alpha-1 undergoes rigorous third-party testing to ensure 99%+ purity and comes with a comprehensive Certificate of Analysis.
Physical Form: Lyophilized Powder
This peptide is provided in lyophilized (freeze-dried) form to ensure maximum stability and shelf life. Reconstitution with an appropriate sterile diluent (bacteriostatic water or sterile water for injection) is required before use. The lyophilization process preserves peptide integrity during storage and transport.
- Reconstitution: Bacteriostatic water recommended for research applications
Research Applications
- Immune system modulation and T-cell activation studies
- Investigation of cytokine production pathways
- Research on adaptive immune response mechanisms
- Studies examining immunosenescence and age-related immune decline
- Hepatitis B and C treatment research models
- Cancer immunotherapy research applications
Mechanism of Action
In research models, Thymosin Alpha-1 demonstrates significant immunomodulatory effects by enhancing T-cell differentiation and activation. It influences the production of various cytokines including interferon-gamma and interleukin-2, while promoting the maturation of T-helper cells and cytotoxic T-lymphocytes. The peptide also exhibits regulatory effects on dendritic cell function and natural killer cell activity.
Molecular Profile
- Chemical Formula: C₁₂₉H₂₁₅N₃₃O₅₅
- Molecular Weight: 3,108.4 Da
- Sequence: Ac-Ser-Asp-Ala-Ala-Val-Asp-Thr-Ser-Ser-Glu-Ile-Thr-Thr-Lys-Asp-Leu-Lys-Glu-Lys-Lys-Glu-Val-Val-Glu-Glu-Ala-Glu-Asn-NH₂
- Purity: >99% (HPLC verified)
- Form: Lyophilized white powder
Laboratory Considerations
- Store lyophilized powder at -20°C for optimal stability
- Once reconstituted, store at 4°C and use within 30 days
- Protect from light and avoid repeated freeze-thaw cycles
- Reconstitution Bacteriostatic water recommended for research applications
- Stable at room temperature for up to 24 months in lyophilized form
Quality Assurance
Each vial of Thymosin Alpha-1 5mg includes:
- Third-party Certificate of Analysis (COA)
- HPLC purity verification
- Mass spectrometry confirmation
FOR RESEARCH PURPOSES ONLY Not for human consumption or medical use
