Semax is a synthetic heptapeptide derived from the adrenocorticotropic hormone (ACTH) fragment ACTH(4-10). Originally developed in Russia for neurological research, this nootropic peptide has been extensively studied for its cognitive enhancement properties and neuroprotective effects. Our research-grade Semax undergoes rigorous third-party testing to ensure 98%+ purity and comes with a comprehensive Certificate of Analysis.
Research Applications
- Cognitive enhancement and memory formation studies
- Neuroprotection and neuroplasticity research
- Investigation of BDNF (Brain-Derived Neurotrophic Factor) pathways
- Stress response and adaptation studies
- Neurodegenerative disease research applications
Mechanism of Action
In research models, Semax demonstrates significant nootropic effects by modulating neurotransmitter systems and promoting neuroplasticity. It enhances the expression of brain-derived neurotrophic factor (BDNF) and nerve growth factor (NGF), while influencing dopaminergic and serotonergic pathways. The peptide also exhibits neuroprotective properties through its effects on oxidative stress reduction and neuronal survival pathways.
Molecular Profile
- Chemical Formula: C₃₇H₅₁N₉O₁₀S
- Molecular Weight: 813.93 Da
- Sequence: Met-Glu-His-Phe-Pro-Gly-Pro
- Purity: >98% (HPLC verified)
- Form: Lyophilized white powder
- Reconstitution: Bacteriostatic water recommended for research applications
Laboratory Considerations
- Store lyophilized powder at -20°C for optimal stability
- Once reconstituted, store at 4°C and use within 30 days
- Protect from light and avoid repeated freeze-thaw cycles
- Use sterile bacteriostatic water or saline for reconstitution
- Stable at room temperature for up to 24 months in lyophilized form
- pH range: 5.0-7.0 when reconstituted
Quality Assurance
Each vial of Semax 10mg includes:
- Third-party Certificate of Analysis (COA)
- HPLC purity verification
- Mass spectrometry confirmation
FOR RESEARCH PURPOSES ONLY Not for human consumption or medical use
