Thymosin Alpha-1 is a synthetic version of the naturally occurring immunomodulatory peptide originally isolated from the thymus gland. This 28-amino acid peptide has been extensively studied for its role in immune system regulation and T-cell function enhancement. Our research-grade Thymosin Alpha-1 undergoes rigorous third-party testing to ensure 99%+ purity and comes with a comprehensive Certificate of Analysis.
Research Applications
- Immune system modulation and T-cell activation studies
- Investigation of cytokine production pathways
- Research on adaptive immune response mechanisms
- Studies examining immunosenescence and age-related immune decline
- Hepatitis B and C treatment research models
- Cancer immunotherapy research applications
Mechanism of Action
In research models, Thymosin Alpha-1 demonstrates significant immunomodulatory effects by enhancing T-cell differentiation and activation. It influences the production of various cytokines including interferon-gamma and interleukin-2, while promoting the maturation of T-helper cells and cytotoxic T-lymphocytes. The peptide also exhibits regulatory effects on dendritic cell function and natural killer cell activity.
Molecular Profile
- Chemical Formula: C₁₂₉H₂₁₅N₃₃O₅₅
- Molecular Weight: 3,108.4 Da
- Sequence: Ac-Ser-Asp-Ala-Ala-Val-Asp-Thr-Ser-Ser-Glu-Ile-Thr-Thr-Lys-Asp-Leu-Lys-Glu-Lys-Lys-Glu-Val-Val-Glu-Glu-Ala-Glu-Asn-NH₂
- Purity: >99% (HPLC verified)
- Form: Lyophilized white powder
Laboratory Considerations
- Store lyophilized powder at -20°C for optimal stability
- Once reconstituted, store at 4°C and use within 30 days
- Protect from light and avoid repeated freeze-thaw cycles
- Reconstitution Bacteriostatic water recommended for research applications
- Stable at room temperature for up to 24 months in lyophilized form
Quality Assurance
Each vial of Thymosin Alpha-1 5mg includes:
- Third-party Certificate of Analysis (COA)
- HPLC purity verification
- Mass spectrometry confirmation
FOR RESEARCH PURPOSES ONLY Not for human consumption or medical use
